THE SMART TRICK OF BET THAT NO ONE IS DISCUSSING

Hemoglobin Brockton [beta 138 (H16) Ala—-Pro] has very low oxygen affinity but electrophoretic mobility and hemolysate binding are regular, suggesting the substitution at beta 138 won't disrupt essential polar interactions, like the hydrogen bonds and salt bridges between Asp 137 and Pro 138, that lead to the cooperative oxygen-binding method in